A key issue for the fabrication of scaffolds for tissue engineering is the development of processing techniques flexible enough to produce materials with a wide spectrum of solubility (bioresorption rates) and mechanical properties matching those of calcified tissues. These techniques must also have the capability of generating adequate porosity to further serve as a framework for cell penetration, new bone formation, and subsequent remodeling. In this work we showed how hybrid organic/inorganic scaffolds with controlled microstructures can be built using robotic assisted deposition at room temperature.

Robocasted composite scaffolds

Publication

[1] Russias J, Saiz E, Deville S, Gryn K, Liu G, Nalla RK, Tomsia AP. Fabrication and in vitro characterization of three-dimensional organic/inorganic scaffolds by robocasting. Journal of Biomedical Materials Research Part A 2007;83:434–445.